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Protein Deimination in Human Health and Disease by Anthony P. Nicholas, Sanjoy K. Bhattacharya & Paul R. Thompson is a book available to read on EtoBox.

What is Protein Deimination in Human Health and Disease about?

Frontmatter 2 1. A History of Deimination Research in Japan: The Founding Fathers 9 2. Aspects of Peptidylarginine Deiminase Regulation that May Predispose to Autoreactivity Against Citrullinated Proteins 23 3. Structures and Functions of Peptidylarginine Deiminases 54 4. The Use of Genetically Engineered Mice to Study PAD Biology and Pathology 73 5. PAD Activation in Arthritis 93 6. Rheumatoid Arthritis: Transition from Systemic Autoimmunity to Joint Inflammation and Bone Loss 120 7. Porphyromonas gingivalis Peptidyl Arginine Deiminase: A Unique Bacterial PAD with Implications for Periodontal Disease and Rheumatoid Arthritis 138 8. Citrullination and Neutrophil Extracellular Traps 189 9. Citrullination and Autophagy 220 10. Antigen Deimination in Human Type 1 Diabetes and Nonobese Diabetic Mice 236 11. Citrullinated Autoantigen Targets as Markers of Extra-Articular Disease in Rheumatoid Arthritis 259 12. The Significance of Myofilament Protein Citrullination in Heart Failure: Citrullination in Cardiovascular Diseases 277 13. Protein Deimination in Protein Misfolding Disorders: Modeled in Human Induced Pluripotent Stem Cells (iPSCs) 307 14. Protein Deimination in Aging and Age-Rela

Author

Anthony P. Nicholas, Sanjoy K. Bhattacharya & Paul R. Thompson

Publisher

Springer International Publishing, Cham

Language

EN