Can I read Interorgan Metabolism of Amino Acids in Human Health and Disease on EtoBox?

Interorgan Metabolism of Amino Acids in Human Health and Disease by Patrick J. Ryan; Steven E. Riechman; James D. Fluckey; Guoyao Wu is a book available to read on EtoBox.

What is Interorgan Metabolism of Amino Acids in Human Health and Disease about?

Amino acids are integral for human health, influencing an array of physiological processes from gene expression to vasodilation to the immune response. In accordance with this expansive range of unique functions, the tissues of the body engage in a complex interplay of amino acid exchange and metabolism to respond to the organism's dynamic needs for a range of nitrogenous products. Interorgan amino acid metabolism is required for numerous metabolic pathways, including the synthesis of functional amino acids like arginine, glutamate, glutamine, and glycine. This physiological process requires the cooperative handling of amino acids by organs (e.g., the small intestine, skeletal muscle, kidneys, and liver), as well as the complete catabolism of nutritionally essential amino acids such as the BCAAs, with their a-ketoacids shuttled from muscle to liver. These exchanges are made possible by several mechanisms, including organ location, as well as the functional zonation of enzymes and the cell-specific expression of amino acid transporters. The cooperative handling of amino acids between the various organs does not appear to be under the control of any centralized regulation, but is ins

Author

Patrick J. Ryan; Steven E. Riechman; James D. Fluckey; Guoyao Wu

Publisher

Springer International Publishing : Imprint: Springer

Published

2021

Language

EN

ISBN

9783030741792

Subjects

Medical, Science, Chemistry