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Catalogue record is a nonfiction available to read on EtoBox.
What is Catalogue record about?
Rational design of AAVrh10-vectored ACE2 functional domain to broadly block the cell entry of SARS-CoV-2 variants 1 1 Introduction 1 2 Materials and methods 2 2.1 Cell lines and viruses 2 2.1.1 Cell lines 2 2.1.2 Viruses 2 2.2 Western blot analyses 2 2.3 Competitive binding experiment 2 2.4 The viral inhibition experiments 2 2.4.1 Neutralization assay based on SARS-CoV-2 pseudovirus 2 2.4.2 Virus inhibition assay based on replication-competent SARS-CoV-2 virus-like-particles (trVLP) 2 2.5 Inhibition of SARS-CoV-2 spike-mediated cell–cell fusion 2 2.6 In silico design of different ACE2 functional domains 2 2.6.1 Protein sequences analysis of ACE2 derived from multiple species 2 2.6.2 Analysis of the inter-molecular interactions 3 2.6.3 Identification of the hot spot residues through alanine scanning 3 2.6.4 Three-dimensional structure prediction and molecular docking 3 2.6.5 Assessment of the physicochemical properties, allergenicity and immunogenicity of the designed peptide candidates 3 2.7 Ex vivo neutralization assay based on mice experiment 3 2.8 Statistical analysis 3 3 Results 3 3.1 AAVrh10-vectored shACE2 and shACE2(PD + Neck) to effectively block the SARS-CoV-2 infections
Who reads Catalogue record?
It is typically read by self-directed learners exploring a subject in depth.
Common subject areas: history, science, philosophy, social sciences.
- Language
- UND
- Category
- nonfiction
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