Assay Sensitivity in “Hybrid Thorough QT/QTc (TQT)” StudyHuang, Dalong PatrickTaylor and Francis Group2018DOI 10.1080/10543406.2018.1535498
Using the Same ICH S7B Assays to Predict TQT Outcome and ProarrhythmiaLeishman, DerekJournal of Pharmacological and Toxicological Methods2017DOI 10.1016/j.vascn.2017.09.104
Thorough QT (TQT) Studies: Concordance with Torsadogenesis and an Evolving Cardiac Safety Testing ParadigmWiśniowska, BarbaraDrug Discovery Today2017DOI 10.1016/j.drudis.2017.04.017
Interdependence of Baseline Correction Method and Covariance Structure for Crossover TQT StudiesLi, WenqingJournal of Biopharmaceutical Statistics2013DOI 10.1080/10543406.2013.735765
Comparative TQT Analysis with Three Fully-automated Platforms: Comparison to Core Laboratory Semi-automated ResultsMeyer, OlivierElsevier Science2013DOI 10.1016/j.jelectrocard.2013.06.002
Association Between Vomiting and QT Hysteresis: Data from a TQT Study with the Endothelin A Receptor Antagonist ClazosentanJuif, Pierre-EricAmerican Association of Pharmaceutical Scientists2020DOI 10.1208/s12248-020-00485-6
Predictive Value of Nonclinical QT Data to Man: Retrospective Database of TQT Studies with Noncardiovascular DrugsDumotier, BerengereElsevier Science2015DOI 10.1016/j.vascn.2015.08.061
Arrhythmogenic Liability Screening in Cardiovascular Safety Pharmacology: Commonality Between Non-clinical Safety Pharmacology and Clinical Thorough QT (TQT) StudiesSimon AuthierElsevier Science2010DOI 10.1016/j.vascn.2010.06.005
The Sodium Glucose Cotransporter 2 Inhibitor Empagliflozin Does Not Prolong QT Interval in a Thorough QT (TQT) StudyArne Ring, Tobias Brand, Sreeraj Macha...BioMed Central2013DOI 10.1186/1475-2840-12-70
The Prospective IQ-CSRC Trial: A Prototype Early Clinical Proarrhythmia Assessment Investigation for Replacing the ICH E14 Thorough QTc (TQT) StudyCavero, IcilioElsevier Science2016DOI 10.1016/j.vascn.2016.02.181
P356 Safety and PK Results of a Thorough QT/QTc (TQT) Study of Orally Administered RPC1063, a Novel, Selective S1P1 Receptor AgonistOlson, A.Journal of Crohn s and Colitis2014DOI 10.1016/s1873-9946(14)60476-1
Lomitapide at Supratherapeutic Plasma Levels Does Not Prolong the QTc Interval-Results from a TQT Study with Moxifloxacin and KetoconazoleDarpo, BorjeJohn Wiley and Sons2013DOI 10.1111/anec.12103