Safety and Antiviral Activity of JTK-652: A Novel HCV Infection Inhibitorde Bruijne · Antiviral Therapy2010PDF438 KB
Preclinical Characterization of JTK-853, a Novel Nonnucleoside Inhibitor of the Hepatitis C Virus RNA-Dependent RNA PolymeraseAndo · American Society for Microbiology2012PDF1.1 MB
JTK-853, a Novel Non-Nucleoside Hepatitis C Virus Polymerase Inhibitor, Demonstrates a High Genetic Barrier to Resistance in vitroAndo · Intervirology2013PDF347 KB
Potent and Selective Inhibition of Tat-Dependent HIV-1 Replication in Chronically Infected Cells by a Novel Naphthalene Derivative JTK-101Wang · Antiviral chemistry & chemotherapy2007PDF353 KB
Broad Antiretroviral Activity and Resistance Profile of the Novel Human Immunodeficiency Virus Integrase Inhibitor Elvitegravir (JTK-303/GS-9137)Shimura · American Society for Microbiology2007PDF270 KB
Genotypic and Phenotypic Analyses of Hepatitis C Virus from Patients Treated with JTK-853 in a Three-Day MonotherapyOgura · American Society for Microbiology2013PDF211 KB
Inhibition of the Tax-Dependent Human T-Lymphotropic Virus Type 1 (HTLV-1) Replication in Persistently Infected Cells by the Naphthalene Derivative JTK-101Wang · Antiviral Research2007PDF60 KB
Antiviral Activity, Pharmacokinetics, and Dose Response of the HIV-1 Integrase Inhibitor GS-9137 (JTK-303) in Treatment-Naive and Treatment-Experienced PatientsDeJesus · JAIDS Journal of Acquired Immune Deficiency Syndromes2006PDF162 KB
941 JTK-652 IS A NOVEL HCV ENTRY INHIBITOR: RESULTS OF A PHASE 1 STUDY EVALUATING SAFETY, TOLERABILITY AND ANTIVIRAL ACTIVITY IN CHRONIC HEPATITIS C PATIENTSBruijne · Journal of Hepatology2009PDF48 KB
Pharmacokinetics, Food Effect, Ketoconazole Interaction, and Safety of JTK-853, a Novel Nonnucleoside HCV Polymerase Inhibitor, After Ascending Single and Multiple Doses in Healthy SubjectsTamaki · Clinical Pharmacology in Drug Development2019PDF1.7 MB
Benzimidazole Derivatives Bearing Substituted Biphenyls as Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors: Structure−Activity Relationship Studies and Identification of a Potent and Highly Selective Inhibitor JTK-109Hirashima · Journal of Medicinal Chemistry2006PDF223 KB
JTK_CYCLE: An Efficient Nonparametric Algorithm for Detecting Rhythmic Components in Genome-Scale Data SetsHughes · Journal of Biological Rhythms2010PDF559 KB