Can I read Protein and Peptide Folding, Misfolding, and Non-Folding on EtoBox?

Protein and Peptide Folding, Misfolding, and Non-Folding by Reinhard Schweitzer-Stenner is a book available to read on EtoBox.

What is Protein and Peptide Folding, Misfolding, and Non-Folding about?

Sheds new light on intrinsically disordered proteins and peptides, including their role in neurodegenerative diseases With the discovery of intrinsically disordered proteins and peptides (IDPs), researchers realized that proteins do not necessarily adopt a well defined secondary and tertiary structure in order to perform biological functions. In fact, IDPs play biologically relevant roles, acting as inhibitors, scavengers, and even facilitating DNA/RNA-protein interactions. Due to their propensity for self-aggregation and fibril formation, some IDPs are involved in neurodegenerative diseases such as Parkinson's and Alzheimer's. With contributions from leading researchers, this text reviews the most recent studies, encapsulating our understanding of IDPs. The authors explain how the growing body of IDP research is building our knowledge of the folding process, the binding of ligands to receptor molecules, and peptide self-aggregation. Readers will discover a variety of experimental, theoretical, and computational approaches used to better understand the properties and function of IDPs. Moreover, they'll discover the role of IDPs in human disease and as drug targets. Protein and Pept

Author

Reinhard Schweitzer-Stenner

Publisher

Hoboken, N.J.: John Wiley & Sons

Published

2012

Language

EN

ISBN

9780470591697

Subjects

Science, Medical, Biology