Can I read Structure-Based Drug Discovery: An Overview (RSC Biomolecular Sciences, Volume 3) on EtoBox?

Structure-Based Drug Discovery: An Overview (RSC Biomolecular Sciences, Volume 3) by Roderick E. Hubbard; Hubbard, R. E; Royal Society of Chemistry (Great Britain) is a book available to read on EtoBox.

What is Structure-Based Drug Discovery: An Overview (RSC Biomolecular Sciences, Volume 3) about?

Structure-based drug discovery is a collection of methods that exploits the ability to determine and analyse the three dimensional structure of biological molecules. These methods have been adopted and enhanced to improve the speed and quality of discovery of new drug candidates. After an introductory overview of the principles and application of structure-based methods in drug discovery, this book then describes the essential features of the various methods. Chapters on X-ray crystallography, NMR spectroscopy, and computational chemistry and molecular modelling describe how these particular techniques have been enhanced to support rational drug discovery, with discussions on developments such as high throughput structure determination, probing protein-ligand interactions by NMR spectroscopy, virtual screening and fragment-based drug discovery. The concluding chapters complement the overview of methods by presenting case histories to demonstrate the major impact that structure-based methods have had on discovering drug molecules. Written by international experts from industry and academia, this comprehensive introduction to the methods and practice of structure-based drug discovery

Author

Roderick E. Hubbard; Hubbard, R. E; Royal Society of Chemistry (Great Britain)

Publisher

Royal Society of Chemistry

Published

2006

Language

EN

ISBN

9781847552549

Subjects

Science, Chemistry, Medical