Can I read Drug Delivery to the Brain : Physiological Concepts, Methodologies and Approaches on EtoBox?

Drug Delivery to the Brain : Physiological Concepts, Methodologies and Approaches by Elizabeth Cunera Maria de Lange; Margareta Hammarlund-Udenaes; Robert G Thorne is a nonfiction available to read on EtoBox.

What is Drug Delivery to the Brain : Physiological Concepts, Methodologies and Approaches about?

The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood–brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and

Who reads Drug Delivery to the Brain : Physiological Concepts, Methodologies and Approaches?

Author

Elizabeth Cunera Maria de Lange; Margareta Hammarlund-Udenaes; Robert G Thorne

Publisher

Springer International Publishing AG

Published

2022

Language

EN

ISBN

9783030887728

Category

nonfiction

Subjects

Science, Technology, Chemistry