Can I read The Pathophysiology of Heart Failure on EtoBox?

The Pathophysiology of Heart Failure by Theresa A. McDonagh; Henry J. Dargie is a book available to read on EtoBox.

What is The Pathophysiology of Heart Failure about?

This chapter reviews the pathophysiology of heart failure by outlining what is known about its key players. These key players include haemodynamic abnormalities, ventricular remodelling, neurohormonal activation, and inflammatory responses. The pathophysiological processes at play in the heart failure syndrome combine to produce a progressive state of reduced myocardial performance, a dilated and/or adversely remodelled heart, and ultimately death from progressive pump failure or ventricular arrhythmia. Except in cases where the myocardial function returns to normal or near normal, neurohormonal blockade leads to some reverse remodelling which does lead to an improved outlook for patients. However, the natural history of heart failure for many patients is that treatment merely serves to delay further deterioration in left ventricular function, which will eventually resume in association with co-morbidities—particularly renal dysfunction—and ultimately lead to progressive multi-organ failure and death.

Author

Theresa A. McDonagh; Henry J. Dargie

Publisher

Oxford University Press

Published

2022

Language

EN