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Cytochrome P-450 [P] structure, mechanism and biochemistry by Thomas J. McMurry, John T. Groves (auth.), Paul R. Ortiz de Montellano (eds.) is a nonfiction available to read on EtoBox.

What is Cytochrome P-450 [P] structure, mechanism and biochemistry about?

Major advances have been made in recent years in clarifying the molecular properties of the cytochrome P-450 system. These advances stem, in practical terms, from the generally recognized importance of cytochrome P-450 in the metabolism of drugs and in the bioactivation of xenobiotics to toxic products. The fascinating multiplicity and differential regulation of cytochrome P-450 isozymes, and their ability to catalyze extraordinarily difficult chemical transformations, have independently drawn many chemists and biochemists into the P-450 circle. Progress in the field, from a technical point of view, has been propelled by the de­ velopment of reliable procedures for the purification of membrane-bound enzymes, by the growing repertoire of molecular biological techniques, and by the development of chemical models that mimic the catalytic action of P-450. As a result, our understanding of the P-450 system is moving from the descriptive, pharmacological level into the tangible realm of atomic detail. The rapid progress and multidisciplinary character of the cytochrome P-450 field, which cuts across the lines that traditionally divide disciplines as diverse as inorganic chemistry and gen

Who reads Cytochrome P-450 [P] structure, mechanism and biochemistry?

Author

Thomas J. McMurry, John T. Groves (auth.), Paul R. Ortiz de Montellano (eds.)

Publisher

Springer US : Imprint : Springer

Published

1986

Language

EN

ISBN

9781475799392

Category

nonfiction

Subjects

Science, Chemistry, Medical