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Protein-Nucleic Acid Interactions: Structural Biology (RSC Biomolecular Sciences, Volume 11) by Phoebe A. Rice and Carl C. Correll is a book available to read on EtoBox.
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<p>The structural biology of protein-nucleic acid interactions is in some ways a mature field and in others in its infancy. High-resolution structures of protein-DNA complexes have been studied since the mid 1980s and a vast array of such structures has now been determined, but surprising and novel structures still appear quite frequently. High-resolution structures of protein-RNA complexes were relatively rare until the last decade. Propelled by advances in technology as well as the realization of RNA's importance to biology, the number of example structures has ballooned in recent years. New insights are now being gained from comparative studies only recently made possible due to the size of the database, as well as from careful biochemical and biophysical studies. As a result of the explosion of research in this area, it is no longer possible to write a comprehensive review. Instead, current review articles tend to focus on particular subtopics of interest. This makes it difficult for newcomers to the field to attain a solid understanding of the basics. One goal of this book is therefore to provide in-depth discussions of the fundamental principles of protein-nucleic acid intera
- Author
- Phoebe A. Rice and Carl C. Correll
- Publisher
- Royal Society of Chemistry
- Published
- 2008
- Language
- EN
- ISBN
- 9781847558268
- Subjects
- Science, Chemistry, Medical
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