Can I read Catalogue record on EtoBox?

Catalogue record is a nonfiction available to read on EtoBox.

What is Catalogue record about?

A sensitive LC-MS/MS method for simultaneous quantification of ulotaront and its N-desmethyl metabolite in human plasma and ... 1 1. Introduction 1 2. Experimental 2 2.1. Chemicals and reagents 2 2.2. Stock solutions, calibration standards and quality control (QC) samples 2 2.3. Solid phase extraction for plasma sample cleanup 2 2.4. LC-MS/MS analysis 2 2.5. Method validation 3 2.6. Application to a clinical PK study: first-in-human single ascending dose study 3 3. Results and discussion 3 3.1. Method development from sample extraction to LC-MS/MS analysis 3 3.2. Validation of the method 4 3.2.1. Selectivity and specificity 4 3.2.2. Calibration curves and sensitivity 5 3.2.3. Intra- and inter-run precision and accuracy and sample dilution linearity 5 3.2.4. Extraction recovery, matrix effect (including hemolysis effect and hyperlipidemic effect), and injector carryover 5 3.2.5. Sample and solution stability 6 3.2.6. Interference tests 6 3.3. Application to first-in-human single ascending dose PK study 6 3.3.1. Clinical study sample measurement and assay performance 6 3.3.2. Pharmacokinetic (PK) analysis and PK parameters 7 4. Conclusion 8 Ethics approval and consent to participate

Who reads Catalogue record?

Language

EN

Category

nonfiction