Can I read The Oncogenomics Handbook (Cancer Drug Discovery and Development) on EtoBox?

The Oncogenomics Handbook (Cancer Drug Discovery and Development) by William J. Larochelle, Richard A. Shimkets is a nonfiction available to read on EtoBox.

What is The Oncogenomics Handbook (Cancer Drug Discovery and Development) about?

Bioinformatic integration of the findings from recent genomic and proteomic research has made possible the development of highly selective therapeutics that can target specific cellular pathways controlling cell proliferation, differentiation, metastasis, evasion of immune surveillance, angiogenesis, and apoptosis. In The Oncogenomics Handbook, a panel of internationally recognized researchers and clinicians provides an integrated overview of cancer drug discovery and development from the bench to the clinic, showing with broad strokes and representative examples the drug development process as a network of linked components leading from the discovered target to the ultimate therapeutic product. Following that path, the authors explain genomic databases and how to discover oncological targets from them, how then to advance from the gene and transcript to the level of protein biochemistry, how next to move from the chemical realm to that of the living cell and, ultimately, pursue animal modeling and clinical development. Emerging cancer therapeutics including rituximab, Herceptin®, AvastinTM, ABGX-EGF, Velcade®, Iressa®, and Zevalin® are addressed. Additional chapters review clinica

Who reads The Oncogenomics Handbook (Cancer Drug Discovery and Development)?

Author

William J. Larochelle, Richard A. Shimkets

Publisher

Humana Press

Published

2005

Language

EN

ISBN

9781588294258

Category

nonfiction

Subjects

Medical, Nursing, Medicine