Can I read Prospective Study of the Effect of Laparoscopic Hemifundoplication on Motor and Sensory Function of the Proximal Stomach on EtoBox?

Prospective Study of the Effect of Laparoscopic Hemifundoplication on Motor and Sensory Function of the Proximal Stomach by M. K. Vu; J. Ringers; J. W. Arndt; C. B. H. W. Lamers; A. A. M. Masclee is a scholarly article available to read on EtoBox.

What is Prospective Study of the Effect of Laparoscopic Hemifundoplication on Motor and Sensory Function of the Proximal Stomach about?

## Abstract ## Background Some 30 per cent of patients develop dyspeptic symptoms following antireflux surgery. These symptoms may result from alterations in the motor and sensory function of the proximal stomach. ## Methods Proximal gastric motor and sensory function was studied with an electronic barostat in 12 patients with reflux who underwent laparoscopic hemifundoplication. In addition, 24-h pHmetry, gastric emptying (scintigraphy) and vagus nerve integrity (pancreatic polypeptide response to hypo-glycaemia) were assessed. Fifteen healthy volunteers served as controls. ## Results Laparoscopic hemifundoplication significantly decreased total acid exposure time (P < 0·05). Vagus nerve function remained intact in all but one patient. The mean(s.e.m.) lag phase for emptying of solids was significantly shorter after operation than before (15(3) versus 21(3) min; P < 0·05). Proximal gastric compliance was not significantly different before and after fundoplication. However, mean(s.e.m.) postprandial relaxation was significantly reduced (P < 0·05) after hemifundoplication compared with the value before operation (3341(1105) versus 12 763(3616) ml over 90 min) and in controls (14 567

Author

M. K. Vu; J. Ringers; J. W. Arndt; C. B. H. W. Lamers; A. A. M. Masclee

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Oxford University Press (OUP) (ISSN 0007-1323)

Published

2000

Language

EN