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The study investigates the role of indole derivatives in alleviating methamphetamine-induced depression and anxiety through the aryl hydrocarbon receptor along the microbiota-brain axis. It finds that meth withdrawal disrupts gut microbiota and reduces indole metabolites, which are linked to mood regulation. The results suggest that targeting the microbiota and indole metabolic pathways may offer new therapeutic strategies for treating meth-related psychological disorders.

Author

scribd

Language

EN