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Search for computational modules in the C. elegans brain by Markus Reigl; Uri Alon; Dmitri B Chklovskii is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Search for computational modules in the C. elegans brain about?

## Background Does the __C. elegans__ nervous system contain multi-neuron computational modules that perform stereotypical functions? We attempt to answer this question by searching for recurring multi-neuron inter-connectivity patterns in the __C. elegans__ nervous system's wiring diagram. ## Results Our statistical analysis reveals that some inter-connectivity patterns containing two, three and four (but not five) neurons are significantly over-represented relative to the expectations based on the statistics of smaller inter-connectivity patterns. ## Conclusions Over-represented patterns (or motifs) are candidates for computational modules that may perform stereotypical functions in the __C. elegans__ nervous system. These modules may appear in other species and need to be investigated further.

Who reads Search for computational modules in the C. elegans brain?

Author

Markus Reigl; Uri Alon; Dmitri B Chklovskii

Publisher

BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, c2003-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc.; Research Square (ISSN 1741-7007)

Published

2004

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)