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Identification and Characterization of Transcription Factors Regulating Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus by Sanjay K. Singh; Barunava Patra; Joshua J. Singleton; Yongliang Liu; Priyanka Paul; Xueyi Sui; Nitima Suttipanta; Sitakanta Pattanaik; Ling Yuan is a book available to read on EtoBox.

What is Identification and Characterization of Transcription Factors Regulating Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus about?

Biosynthesis of the therapeutically valuable terpenoid indole alkaloids (TIAs), in the medicinal plant Catharanthus roseus, is one of the most elaborate and complex metabolic processes. Although genomic and transcriptomic resources have significantly accelerated gene discovery in the TIA pathway, relatively few genes of transcription factors (TFs) have been identified and characterized thus far. Systematic identification of TFs and elucidation of their functions are crucial for understanding TIA pathway regulation. The successful discovery of TFs in the TIA pathway has relied mostly on three different approaches, (1) identification of cis-regulatory motifs (CRMs) present in the pathway gene promoters as they often provide clues on potential TFs that bind to the promoters, (2) co-expression analysis, based on the assumption that TFs regulating a metabolic or developmental pathway exhibit similar spatiotemporal expression as the pathway genes, and (3) isolation of homologs of TFs known to regulate structurally similar or diverse specialized metabolites in different plant species. TFs regulating TIA pathway have been isolated using either an individual or a combination of the three ap

Author

Sanjay K. Singh; Barunava Patra; Joshua J. Singleton; Yongliang Liu; Priyanka Paul; Xueyi Sui; Nitima Suttipanta; Sitakanta Pattanaik; Ling Yuan

Publisher

Springer US : Imprint : Humana

Published

2022

Language

EN

ISBN

9781071623480

Subjects

Science, Stem