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Depressants have a long history dating back to 1832 when chloral hydrate was first used as a sedative. Common short term effects of depressants include slowed brain function, breathing, and blood pressure as well as dizziness and difficulty concentrating. Long term effects can include addiction, impaired sexual function, and respiratory issues. Depressants work by increasing the neurotransmitter GABA in the brain to produce a calming effect. Withdrawal from long term use can cause insomnia, agitation, and h

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