Can I read INVOLVEMENT OF PI 3‐KINASE, PKA AND PKC IN PDGF‐ AND TGF‐β‐MEDIATED PREVENTION OF 2‐DEOXY‐D‐RIBOSE‐INDUCED APOPTOSIS IN THE INSECT CELL LINE, IPLB‐LdFB on EtoBox?
INVOLVEMENT OF PI 3‐KINASE, PKA AND PKC IN PDGF‐ AND TGF‐β‐MEDIATED PREVENTION OF 2‐DEOXY‐D‐RIBOSE‐INDUCED APOPTOSIS IN THE INSECT CELL LINE, IPLB‐LdFB by Enzo Ottaviani; Daniela Barbieri; Davide Malagoli; Dimitris Kletsas is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is INVOLVEMENT OF PI 3‐KINASE, PKA AND PKC IN PDGF‐ AND TGF‐β‐MEDIATED PREVENTION OF 2‐DEOXY‐D‐RIBOSE‐INDUCED APOPTOSIS IN THE INSECT CELL LINE, IPLB‐LdFB about?
Activation of phosphatidylinositol (PI) 3‐kinase, protein kinase A (PKA) and protein kinase C (PKC) is associated with the survival effect elicited by PDGF‐AB and TGF‐β1 against the apoptotic inducer 2‐deoxy‐D‐ribose (dRib) in the fat body cell line, IPLB‐LdFB, from the insect __Lymantria dispar__. dRib induces apoptosis and provokes mitochondrial membrane depolarization (MMD). The antioxidant __N__ ‐acetyl‐L‐cysteine annuls only the first effect. These findings suggest that apoptosis and MMD are provoked by two different mechanisms, and that dRib induces apoptosis by oxidative stress.
Who reads INVOLVEMENT OF PI 3‐KINASE, PKA AND PKC IN PDGF‐ AND TGF‐β‐MEDIATED PREVENTION OF 2‐DEOXY‐D‐RIBOSE‐INDUCED APOPTOSIS IN THE INSECT CELL LINE, IPLB‐LdFB?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Enzo Ottaviani; Daniela Barbieri; Davide Malagoli; Dimitris Kletsas
- Publisher
- Elsevier Science; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley (ISSN 1065-6995)
- Published
- 2001
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)