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The document outlines a Phase I/II clinical trial protocol for a combination immunotherapy aimed at generating HER-2/neu specific cytotoxic T cells in patients with HER2 overexpressing Stage IV breast and ovarian cancers. The study will evaluate the safety and immune response to a HER2 peptide-based vaccine administered alongside maintenance trastuzumab. The trial aims to enroll 20 patients and assess overall survival as a secondary endpoint, while focusing on the potential synergistic effects of the treatm
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- samin.edu047
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- EN