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Association between serum 25-hydroxyvitamin D and vitamin D dietary supplementation and risk of all-cause and cardiovascular mortality among adults with hypertension by Haowen Ye; Yexin Li; Shaomin Liu; Xiaofang Zhang; Huanzhu Liang; Ying Wang; Ruxin Wang; Han Liu; Yun Wen; Chunxia Jing; Lihong Wang is a Medicine article available to read on EtoBox.

What is Association between serum 25-hydroxyvitamin D and vitamin D dietary supplementation and risk of all-cause and cardiovascular mortality among adults with hypertension about?

## Background The relationship between vitamin D status and mortality among adults with hypertension remains unclear. ## Methods This prospective cohort study involved a sample of 19,500 adults with hypertension who participated in the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2018. We utilized a weighted COX proportional hazard model to assess the association between vitamin D status and mortality. This statistical model calculates hazard ratios (HR) and their corresponding 95% confidence intervals (95% CI). ## Results The study indicated that lower serum 25(OH)D concentration was associated with an increased risk of all-cause mortality among individuals with hypertension. Specially. Those with concentrations between 25.0 and 49.9 nmol/L (HR = 1.71, 95%CI = 1.22–2.40) and less than 25.0 nmol/L (HR = 1.97, 95%CI = 1.15–3.39) had higher hazard ratios for all-cause mortality. Individuals with hypertension who took vitamin D supplements had a lower risk of all-cause mortality, but not the risk of CVD mortality (HR 0.75, 95%CI 0.54–1.03), compared to those who did not supplement (HR = 0.76, 95%CI = 0.61–0.94). Subgroup analysis further revealed that vitamin

Who reads Association between serum 25-hydroxyvitamin D and vitamin D dietary supplementation and risk of all-cause and cardiovascular mortality among adults with hypertension?

Author

Haowen Ye; Yexin Li; Shaomin Liu; Xiaofang Zhang; Huanzhu Liang; Ying Wang; Ruxin Wang; Han Liu; Yun Wen; Chunxia Jing; Lihong Wang

Publisher

BioMed Central

Published

2024

Language

EN

Field

Medicine (Health Sciences)