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Can I read Biomimetic Smart Nanoplatform for Dual Imaging-guided Synergistic Cancer Therapy on EtoBox?
Biomimetic Smart Nanoplatform for Dual Imaging-guided Synergistic Cancer Therapy by Zhengzou Fang; Erli Yang; Ying Du; Daqing Gao; Guoqiu Wu; Yuanjian Zhang; Yanfei Shen is a Materials Science article available to read on EtoBox.
What is Biomimetic Smart Nanoplatform for Dual Imaging-guided Synergistic Cancer Therapy about?
Developing an integrated multimodal diagnosis and therapeutics nanoplatform is of great importance to enhance the outcome of cancer therapy. Herein, we report a highly efficient and biocompatible nanoplatform based on the assembly of a graphene oxide (GO) and metal-organic framework (MOF) Fe-porphyrin, which was coated with a folate-functionalized erythrocyte membrane (FA-EM@GO-MOF). The nanoplatform could be targeted to cancer cells precisely, and could avoid immune elimination and had prolonged blood circulation due to the presence of FA-EM on its surface. The presence of GO and paramagnetic Fe ions endowed the nanoplatform with robust fluorescence imaging and -weighted magnetic resonance imaging capacities. The porous structure and large surface area of GO-MOF make it desirable for drug delivery in chemotherapy. More importantly, with one operation, under the same laser (808 nm) irradiation, both photothermal therapy and photodynamic therapy could be triggered for efficient synergistic treatment by using MOF as a photosensitizer. This synergistic anticancer therapy promoted the generation of tumor-associated antigens and evoked an antitumor immune response. and therapy studies h
Who reads Biomimetic Smart Nanoplatform for Dual Imaging-guided Synergistic Cancer Therapy?
It is typically read by researchers, students, and practitioners in Materials Science.
- Author
- Zhengzou Fang; Erli Yang; Ying Du; Daqing Gao; Guoqiu Wu; Yuanjian Zhang; Yanfei Shen
- Published
- 2022
- Language
- EN
- Field
- Materials Science (Physical Sciences)