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Linkage of mother–baby pairs in the German Pharmacoepidemiological Research Database by Edeltraut Garbe; Marc Suling; Sebastian Kloss; Christina Lindemann; Ulrike Schmid is a Medicine article available to read on EtoBox.

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## Abstract ## Purpose Administrative healthcare databases are increasingly being used to investigate potential drug risks in pregnancy. Our study aimed to develop an algorithm for linkage of mother–baby pairs (MBPs) in the German Pharmacoepidemiological Research Database (GePaRD) as a prerequisite for such studies. ## Methods GePaRD contains sociodemographic data, drug dispensations, ambulatory, and hospital information on more than 14 million insurants from four German statutory health insurances (SHIs) covering all regions in Germany. Linkage was based on co‐insurance information of the newborn with the potential mother (direct linkage) or of both potential mother and newborn with the potential father (indirect linkage). Linkage is not possible if the baby is co‐insured with the father and the mother is self‐insured. Further information on birth or childbed was used to validate the potential mother as true mother in MBP. Descriptive comparisons between linked and unlinked mothers were conducted. ## Results Of 323 993 newborns identified between 2004 and 2006, 250 355 (77.3%) could be linked in MBP. Of those, 189 702 (75.8%) MBP were based on direct linkage. Mean age was similar

Who reads Linkage of mother–baby pairs in the German Pharmacoepidemiological Research Database?

Author

Edeltraut Garbe; Marc Suling; Sebastian Kloss; Christina Lindemann; Ulrike Schmid

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-8569)

Published

2010

Language

EN

Field

Medicine (Health Sciences)