Can I read High Field Asymmetric Waveform Ion Mobility Spectrometry-mass Spectrometry: an Investigation of Leucine Enkephalin Ions Produced by Electrospray Ionization on EtoBox?

High Field Asymmetric Waveform Ion Mobility Spectrometry-mass Spectrometry: an Investigation of Leucine Enkephalin Ions Produced by Electrospray Ionization by Roger Guevremont; Randy W. Purves is a Chemistry article available to read on EtoBox.

What is High Field Asymmetric Waveform Ion Mobility Spectrometry-mass Spectrometry: an Investigation of Leucine Enkephalin Ions Produced by Electrospray Ionization about?

High field asymmetric waveform ion mobility spectrometry (FAIMS) provides atmospheric pressure, room temperature, low-resolution separation of gas-phase ions. The FAIMS analyzer acts as an ion filter that can continuously transmit one type of ion, independent of m/z. The combination of FAIMS with electrospray ionization and mass spectrometry (ESI-FAIMS-MS) is a powerful technique and is used in this study to investigate the cluster ions of leucine enkephalin (YGGFL). Separation by FAIMS of leucine enkephalin ions having the same m/z (m/z 556.5), [M + H](+) and [2M + 2H](2+), was observed. In addition, four complex ions of leucine enkephalin, [2M + H](+), [4M + 2H](2+), [6M + 3H](3+), and [8M + 4H](4+), all having m/z 1112, were shown to be separated in FAIMS. Fragmentation of ions as the result of harsh conditions within the mass spectrometer interface (FAIMS-MS) was shown to provide similar information to that obtained from MS/MS experiments in conventional ESI-MS.

Who reads High Field Asymmetric Waveform Ion Mobility Spectrometry-mass Spectrometry: an Investigation of Leucine Enkephalin Ions Produced by Electrospray Ionization?

Author

Roger Guevremont; Randy W. Purves

Publisher

Elsevier Science; Springer-Verlag; Springer New York LLC; American Chemical Society (ACS); Springer Science and Business Media LLC; Elsevier BV (ISSN 1044-0305)

Published

1999

Language

EN

Field

Chemistry (Physical Sciences)