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Chromosomal Constitution of Nucleolus-associated Chromatin in Man by A. Stahl; M. Hartung; A. M. Vagner-Capodano; C. Fouet is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Chromosomal Constitution of Nucleolus-associated Chromatin in Man about?

Use of specific stains permits analysis of the frequency of nucleolus-associated heterochromatin in chromosomes 1 and 9 from human fibroblasts. In 81 per cent of interphase nuclei the heterochromatic segment of both No. 1 chromosomes is associated with the nucleolus, while in 19 per cent only one heterochromatic segment shows such an association with the other occupying a random position in the nucleoplasm. The nucleolar association of chromosome 9 heterochromatin is less constant: in 42.3 per cent of the nuclei both segments are associated with the nucleolus, in 39 per cent of the nuclei only one heterochromatic segment presents such an association, and in 18.7 per cent neither of the two heterochromatic segments is in nucleolar association. In 6 per cent of the cells, one or two chromosome 9 heterochromatic segments are in contact with the nuclear membrane. In situ hybridization using tritium-labeled 28S and 18S RNA shows that in the interphase nucleus the acrocentric short arms, carriers of ribosomal cistrons, are associated with the nucleolus. These observations demonstrate the complexity of the nucleolus-associated chromatin which, in addition to segments of chromosomes 1, 9,

Who reads Chromosomal Constitution of Nucleolus-associated Chromatin in Man?

Author

A. Stahl; M. Hartung; A. M. Vagner-Capodano; C. Fouet

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-6717)

Published

1976

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)