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Term planned delivery based on fetal growth assessment with or without the cerebroplacental ratio in low-risk pregnancies (RATIO37): an international, multicentre, open-label, randomised controlled trial by Marta Rial-Crestelo; Marek Lubusky; Mauro Parra-Cordero; Ladislav Krofta; Anna Kajdy; Eyal Zohav; Elena Ferriols-Perez; Rogelio Cruz-Martinez; Marian Kacerovsky; Elena Scazzocchio; Lucie Roubalova; Pamela Socias; Lubomir Hašlík; Jan Modzelewski; Eran Ashwal; Julia Castellá-Cesari; Monica Cruz-Lemini; Eduard Gratacos; Francesc Figueras; Annalisa Cancemi; Mariella Giannone; Ana Rosy Velasco-Santiago; Beatriz Sánchez-Hoyo; Nora Izquierdo-Sánchez; Cristina Cobos-Serrano; Sonia Matías-Ponce; Sonia Mayordomo-Gallardo; Alicia Castejón-Abad; Raigam-Jafet Martinez-Portilla; Esther Crespo-Mirasol; Carmen España-Calancha; Beatriz Lorente-Silva; Marta Herrera-Julve; Rocío Astudillo-Alonso; Ilaria Bianchi; Alex Biterna-Tejeiro; Vladimira Kroutilova; Veronika Kolarova; Katerina Hermanova; Veronika Durdova; Tereza Kratochvilova; Michaela Maderkova-Tozzi; Álvaro Sepulveda-Martinez; Luis Aravena; Javiera Urquieta; Katerina Macková; Anna Brandejsová; Monika Jakubiak-Proć; Sys Dorota; Katarzyna Muzyka-Placzyńska; Michal Rabijewski; Beata Mazur; Lucasz Jóźwiak; Dagmara Filipecka-Tyczka; Krzysztof Berbeka; Lucasz Pydyś; Ilan Gull; Nina Krajden Haratz; Gustavo Malinger; José-Luis Hernández-Sánchez; María Prat-Om; Ricardo Rubio-Salazar; Carolina Rueda-García; Maite López-Yarto-Elejabeitia; Paula-Daniela Diaz-Rodríguez; Antoni Payà-Panadés; Sophie Buob; Erika Ros-de-los-Santos; Andrea Garriga-Parra; Margalida-Esperanza Sastre-Cuadri; Miguel Martínez-Rodríguez; Rosa Villalobos-Gómez; Hugo López-Briones; Eréndira Chávez-González is a Social Sciences article available to read on EtoBox.
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## Background The cerebroplacental ratio is associated with perinatal mortality and morbidity, but it is unknown whether routine measurement improves pregnancy outcomes. We aimed to evaluate whether the addition of cerebroplacental ratio measurement to the standard ultrasound growth assessment near term reduces perinatal mortality and severe neonatal morbidity, compared with growth assessment alone. Methods RATIO37 was a randomised, open-label, multicentre, pragmatic trial, conducted in low-risk pregnant women, recruited from nine hospitals over six countries. The eligibility criteria were designed to be broad; participants were required to be 18 years or older, with an ultrasound-dated confirmed singleton pregnancy in the first trimester, an alive fetus with no congenital malformations at the routine second-trimester ultrasound, an absence of adverse medical or obstetric history, and the capacity to give informed consent. Women were randomly assigned in a 1:1 ratio (block size 100) using a web-based system to either the concealed group or revealed group. In the revealed group, the cerebroplacental ratio value was known by clinicians, and if below the fifth centile, a planned deliv
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- Author
- Marta Rial-Crestelo; Marek Lubusky; Mauro Parra-Cordero; Ladislav Krofta; Anna Kajdy; Eyal Zohav; Elena Ferriols-Perez; Rogelio Cruz-Martinez; Marian Kacerovsky; Elena Scazzocchio; Lucie Roubalova; Pamela Socias; Lubomir Hašlík; Jan Modzelewski; Eran Ashwal; Julia Castellá-Cesari; Monica Cruz-Lemini; Eduard Gratacos; Francesc Figueras; Annalisa Cancemi; Mariella Giannone; Ana Rosy Velasco-Santiago; Beatriz Sánchez-Hoyo; Nora Izquierdo-Sánchez; Cristina Cobos-Serrano; Sonia Matías-Ponce; Sonia Mayordomo-Gallardo; Alicia Castejón-Abad; Raigam-Jafet Martinez-Portilla; Esther Crespo-Mirasol; Carmen España-Calancha; Beatriz Lorente-Silva; Marta Herrera-Julve; Rocío Astudillo-Alonso; Ilaria Bianchi; Alex Biterna-Tejeiro; Vladimira Kroutilova; Veronika Kolarova; Katerina Hermanova; Veronika Durdova; Tereza Kratochvilova; Michaela Maderkova-Tozzi; Álvaro Sepulveda-Martinez; Luis Aravena; Javiera Urquieta; Katerina Macková; Anna Brandejsová; Monika Jakubiak-Proć; Sys Dorota; Katarzyna Muzyka-Placzyńska; Michal Rabijewski; Beata Mazur; Lucasz Jóźwiak; Dagmara Filipecka-Tyczka; Krzysztof Berbeka; Lucasz Pydyś; Ilan Gull; Nina Krajden Haratz; Gustavo Malinger; José-Luis Hernández-Sánchez; María Prat-Om; Ricardo Rubio-Salazar; Carolina Rueda-García; Maite López-Yarto-Elejabeitia; Paula-Daniela Diaz-Rodríguez; Antoni Payà-Panadés; Sophie Buob; Erika Ros-de-los-Santos; Andrea Garriga-Parra; Margalida-Esperanza Sastre-Cuadri; Miguel Martínez-Rodríguez; Rosa Villalobos-Gómez; Hugo López-Briones; Eréndira Chávez-González
- Publisher
- Elsevier BV
- Published
- 2024
- Language
- EN
- Field
- Social Sciences