Opening book details…
Can I read Initial characterization of STS markers in the LSXSS series of recombinant inbred strains on EtoBox?
Initial characterization of STS markers in the LSXSS series of recombinant inbred strains by P. D. Markel; T. E. Johnson is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Initial characterization of STS markers in the LSXSS series of recombinant inbred strains about?
We are mapping quantitative trait loci (QTLs) that influence ethanol-induced anesthesia (sleep time) in the Long-sleep (LS) and Short-sleep (SS) selected lines of mice. Fifty microsatellite-STS markers were initially screened for simple-sequence length polymorphisms between the LS and SS lines. Nineteen markers were polymorphic. Eleven markers unequivocally differentiated the LS and SS lines and were used to establish strain distribution patterns for the LSXSS series of recombinant inbred strains. Five markers each accounted for at least 5% of sleep-time genetic variance among the RI strains. Linkage of provisional QTLs detected among RIs will be confirmed or disproved in a large F z population. This ongoing QTLmapping project eventually will result in a strain distribution pattern for the LSXSS RI series with an average marker spacing of 5 centimorgans.
Who reads Initial characterization of STS markers in the LSXSS series of recombinant inbred strains?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- P. D. Markel; T. E. Johnson
- Publisher
- Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Springer Nature (ISSN 0938-8990)
- Published
- 1994
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)