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Can I read FDA-Approved Inhibitors for SARS-CoV-2 PLpro on EtoBox?
FDA-Approved Inhibitors for SARS-CoV-2 PLpro by tthuan is a document available to read on EtoBox.
What is FDA-Approved Inhibitors for SARS-CoV-2 PLpro about?
This research article identifies seven FDA-approved drugs as potential inhibitors of the SARS-CoV-2 papain-like protease (PLpro) using a multi-phase in silico approach. The study screened 3009 FDA-approved drugs, confirming the binding of selected compounds, particularly Celecoxib, to the active pocket of PLpro. The findings suggest a feasible strategy for drug repurposing against COVID-19, although further validation through in vitro and in vivo studies is necessary.
- Author
- tthuan
- Language
- EN