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Altered Cellular Responsiveness During Ageing by Suresh I. S. Rattan; Anastassia Derventzi is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Altered Cellular Responsiveness During Ageing about?

## Abstract The capacity of cells and organisms to respond to external stimuli and to maintain stability in order to survive decreases progressively during ageing. The mitogenic and stimulatory effects of growth factors, hormones and other agents are reduced significantly during cellular ageing. The sensitivity of ageing cells to toxic agents including antibiotics, phorbol esters, radiations and heat shock increases. This failure of homeostasis during cellular ageing does not appear to be due to any quantitative and qualitative defects in the receptor systems. Instead, metabolic defects in the pathways of macromolecular synthesis may be the basis of altered cellular responsiveness during ageing.

Who reads Altered Cellular Responsiveness During Ageing?

Author

Suresh I. S. Rattan; Anastassia Derventzi

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0265-9247)

Published

1991

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)