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This review discusses the engineering of bacteriophages to enhance their host range and efficacy against multidrug-resistant bacteria. It highlights the importance of understanding bacteriophage-bacteria interactions and presents various gene editing techniques, including CRISPR-Cas and homologous recombination, to modify phage receptor-binding proteins. The review emphasizes the potential of phage therapy as a promising alternative to antibiotics by leveraging advanced engineering methods to overcome limit

Author

mtchaudhry16

Language

EN