About this document
Allosteric Disulfides and Prestress Analysis by Parvinder McCartney is a document available to read on EtoBox.
This document discusses how certain types of disulfide bonds called allosteric disulfides may act as mechanical switches in proteins by storing torsional strain. Through molecular dynamics simulations and statistical analysis of protein structures, the researchers found evidence that two types of disulfide bonds called RHStaples and RHHooks experience higher levels of prestress than other disulfide bonds, with forces of around 200 piconewtons. This prestress could allow the reactivity of these disulfide bon
- Author
- Parvinder McCartney
- Language
- EN