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Absite Topic Review General Surgery Nir Hus, MD, PhD. Mount Sinai Medical Center Miami Beach Topics   1) BRCA-1,2.   2) Rx Postop Parotitis.   3) Rx Non-healing burn wound. Nir Hus Predict Increased risk BRCA-1,2 mutation   BRCA I  Ovarian CA – 40% lifetime risk  Male Breast CA – 1% lifetime risk   BRCA II  Ovarian CA – 10% lifetime risk  Male Breast CA – 10% lifetime risk Nir Hus BRCA cont.   BRCA gene + family Hx = 60% lifetime risk of breast CA (autosomal dominant) 

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