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Performance of 2020 AHA/ACC HCM Guidelines and Incremental Value of Myocardial Strain for Predicting SCD by Hyun-Jung Lee; Hyung-Kwan Kim; Sang Chol Lee; Jihoon Kim; Jun-Bean Park; Seung-Pyo Lee; Yong-Jin Kim is a Medicine article available to read on EtoBox.

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## Background The 2020 American Heart Association (AHA)/American College of Cardiology (ACC) guidelines for sudden cardiac death (SCD) risk stratification in hypertrophic cardiomyopathy (HCM) need further international validation. ## Objectives Performance of the guidelines and the incremental value of myocardial strain for predicting SCD in HCM were investigated. ## Methods In 1,416 HCM patients, SCD risk was stratified according to the 2020 AHA/ACC and 2014 European Society of Cardiology (ESC) guidelines. Left ventricular (LV) global longitudinal strain (GLS) and left atrial reservoir strain (LARS) were measured. The main outcome consisted of SCD events. ## Results Overall, 29.1% had major risk factors (RFs), and 14.7% had nonmajor RFs in the absence of major RFs; estimated 5-year SCD event rates were 6.8% and 2.3%, respectively. SCD risk was significantly increased in the former group but not in the latter. When stratified by the number of RFs, 5-year SCD event rates were 1.9%, 3.0%, 4.9%, and 18.4% for patients with 0, 1, 2, and 3 or more RFs, respectively. SCD risk was elevated in patients with multiple RFs but not in those with a single RF. Performance of the AHA/ACC and ESC

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Author

Hyun-Jung Lee; Hyung-Kwan Kim; Sang Chol Lee; Jihoon Kim; Jun-Bean Park; Seung-Pyo Lee; Yong-Jin Kim

Publisher

Elsevier

Published

2023

Language

EN

Field

Medicine (Health Sciences)