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The document discusses the deconstruction of morphine by removing different ring structures. Removing ring E from morphine results in a κ-opioid agonist with μ-opioid agonist activity. Removing rings B, C, and E produces a μ-opioid agonist. Removing rings B, C, D, and E yields a structure modified 4-phenylpiperidine derivative that is a μ-opioid antagonist. The document also briefly discusses various derivatives of morphine including pethidine, fentanyl, and methadone that have analgesic properties with red

Author

Shamael Alsharif

Language

EN