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This document summarizes the benefits of SGLT-2 inhibitors for treating heart failure. It discusses how SGLT-2 inhibitors work through multiple mechanisms like reducing preload and afterload. Large clinical trials showed they reduced cardiovascular risks and heart failure hospitalizations in patients with reduced ejection fraction regardless of diabetes status. Guidelines now recommend SGLT-2 inhibitors for diabetes, kidney disease, and heart failure. However, real-world use remains low despite strong evide

Author

Hnin

Language

EN