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Cardiovascular Causes For Sudden Infant Death by Marie Valdés-Dapena; Enid Gilbert-Barness is a Medicine article available to read on EtoBox.

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croscopic sections. Because the etiology is usually viral, the in£ammatory cells are uniformly lymphocytes. Although bacteria and fungi also may cause in£ammation of infant heart muscle, they do so only rarely [1]. In babies in the ¢rst year of life, the Coxsackievirus, especially group B3, and Toxoplasma gondii are often the agents involved. Coxsackie B myocarditis is most prevalent in the summer and early autumn and most often a¡ects the infant in the ¢rst month of life. The onset of the disease is sudden, and the infant may have an elevated or subnormal temperature. Some infants recover completely, but for others the course may be rapidly fatal. It is this group that presents as apparent sudden infant death syndrome (SIDS) [2,3]. At autopsy, the heart may be enlarged and=or heavy, and there may be petechiae in the epicardium and myocardium. However, upon gross inspection the heart often appears entirely normal. The ¢rst obvious pathological feature seen upon histologic inspection is the presence of many lymphocytes between muscle ¢bers (F|gure 1). The lymphocytes may be accompanied by histiocytes and plasma cells. Necrosis of individual myocardial ¢bers also is present and in so

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Author

Marie Valdés-Dapena; Enid Gilbert-Barness

Publisher

Informa UK Limited

Published

2002

Language

EN

Field

Medicine (Health Sciences)