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Cavity lining after excavating caries lesions: Meta-analysis and trial sequential analysis of randomized clinical trials by Falk Schwendicke; Gerd Göstemeyer; Christian Gluud is a Dentistry article available to read on EtoBox.

What is Cavity lining after excavating caries lesions: Meta-analysis and trial sequential analysis of randomized clinical trials about?

## Objectives: After removal of dentine caries lesions, cavity lining has been advocated. non-clinical data support this approach, but clinical data are sparse and ambiguous. we aimed at evaluating the benefits and harms of cavity lining using meta-analysis and trial sequential analysis. ## Data: We included randomized clinical trials comparing restorations without versus with cavity lining for treating primary caries lesions. only trials reporting failure (defined as need to re-retreat) after ≥1 year follow-up were included. trial selection, data extraction, and risk of bias assessment were conducted independently by two reviewers. we conducted random-effects intention-to-treat and per-protocol meta-analyses, and trial sequential analysis to control for random errors. ## Sources: Electronic databases (pubmed, embase, central) were systematically screened, and hand searches and cross-referencing performed. ## Study selection: From 128 studies, three randomized trials (89/130 patients or teeth), all treating primary teeth, were included. the trials had high risk of bias. all trials compared no lining versus calcium hydroxide lining after selective caries removal followed by adhesive

Who reads Cavity lining after excavating caries lesions: Meta-analysis and trial sequential analysis of randomized clinical trials?

Author

Falk Schwendicke; Gerd Göstemeyer; Christian Gluud

Publisher

Elsevier BV

Published

2015

Language

EN

Field

Dentistry (Health Sciences)