Can I read Value of Blood Pool Contrast Agents in Magnetic Resonance Angiography of the Pelvis and Lower Extremities on EtoBox?

Value of Blood Pool Contrast Agents in Magnetic Resonance Angiography of the Pelvis and Lower Extremities by M. Saeed; M. F. Wendland; M. Engelbrecht; H. Sakuma; C. B. Higgins is a Medicine article available to read on EtoBox.

What is Value of Blood Pool Contrast Agents in Magnetic Resonance Angiography of the Pelvis and Lower Extremities about?

Our objective was: (1) to determine the appropriate dose of new ultrasmall superparamagnetic iron oxide particles for magnetic resonance angiography (MRA). This agent comprised of a single iron oxide crystal stabilized with a carbohydrate-polyethylene glycol coat (PEG-Ferron/NC 100150 injection); (2) to determine the proper flip angle for PEG-Ferron-enhanced 3 D time-of-flight (TOF) MRA sequence; and (3) to compare the enhancement of peripheral vessels following PEG-Ferron and GdDTPA-BMA. MRA parameters were: TR/ TE = 50/2.1 ms, NEX = 1, FOV = 30 30 1.8 cm, and matrix = 256 128 64. In anesthetized beagle dogs (n = 10), the effects of PEG-Ferron and GdDTPA-BMA on regional signal were monitored for 45 min and compared. The lowest dose of PEG-Ferron (0.05 mmol/kg) produced the best enhancement of primary, secondary and tertiary vessels. The flip angle 60 provided better enhancement than 20 on contrast enhanced images. Unlike GdDTPA-BMA, PEG-Ferron allowed prolonged delineation (> 45 min) of the pelvis and lower extremities circulation. PEG-Ferron provided greater Contrast-to-noise ratio CNR (80.2 6.2, P < 0.05) than GdDTPA-BMA (63.5 ± 2.5). It may be possible for blood pool contrast-e

Who reads Value of Blood Pool Contrast Agents in Magnetic Resonance Angiography of the Pelvis and Lower Extremities?

Author

M. Saeed; M. F. Wendland; M. Engelbrecht; H. Sakuma; C. B. Higgins

Publisher

Springer Science and Business Media LLC

Published

1998

Language

EN

Field

Medicine (Health Sciences)