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The document describes the isolation and characterization of three new dimeric alkaloids - leurocolombine, vinamidine, and pseudovincaleukoblastine diol - from the plant Catharanthus roseus. Leurocolombine was isolated through gradient pH purification and preparative techniques. Its structure was elucidated through UV, IR, NMR, and mass spectroscopy. Vinamidine was isolated through preparative HPLC. Pseudovincaleukoblastine diol was identified through NMR and mass spectroscopy. Leurocolombine showed antimit
- Author
- Tina Andayani
- Language
- EN