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Can I read Relationship Between Thiazolidinedione Use and Cardiovascular Outcomes and All‐cause Mortality Among Patients with Diabetes: a Time‐updated Propensity Analysis on EtoBox?
Relationship Between Thiazolidinedione Use and Cardiovascular Outcomes and All‐cause Mortality Among Patients with Diabetes: a Time‐updated Propensity Analysis by Zeina A. Habib; Leonidas Tzogias; Suzanne L. Havstad; Karen Wells; George Divine; David E. Lanfear; Jeffrey Tang; Richard Krajenta; Manel Pladevall; L. Keoki Williams is a Medicine article available to read on EtoBox.
What is Relationship Between Thiazolidinedione Use and Cardiovascular Outcomes and All‐cause Mortality Among Patients with Diabetes: a Time‐updated Propensity Analysis about?
## Abstract ## Purpose To investigate the association of the thiazolidinediones (TZDs), rosiglitazone, and pioglitazone, together and individually on the risk of cardiovascular outcomes and all‐cause mortality, using time‐updated propensity score adjusted analysis. ## Methods We conducted a retrospective cohort study in a large vertically integrated health system in southeast Michigan. Cohort inclusion criteria included adult patients with diabetes treated with oral medications and followed longitudinally within the health system between 1 January 2000 and 1 December 2006. The primary outcome was fatal and non‐fatal acute myocardial infarction (AMI). Secondary outcomes included hospitalizations for congestive heart failure (CHF), fatal, and non‐fatal cerebrovascular accidents (CVA) and transient ischemic attacks (TIA), combined coronary heart disease (CHD) events, and all‐cause mortality. ## Results 19 171 patients were included in this study. Use of TZDs (adjusted hazard ratio (aHR) with propensity adjustment (PA), 0.92; 95% confidence interval (CI) 0.73–1.17), rosiglitazone (aHR with PA, 1.06; 95%CI 0.66–1.70), and pioglitazone (aHR with PA, 0.91; 95%CI 0.69–1.21) was not associa
Who reads Relationship Between Thiazolidinedione Use and Cardiovascular Outcomes and All‐cause Mortality Among Patients with Diabetes: a Time‐updated Propensity Analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Zeina A. Habib; Leonidas Tzogias; Suzanne L. Havstad; Karen Wells; George Divine; David E. Lanfear; Jeffrey Tang; Richard Krajenta; Manel Pladevall; L. Keoki Williams
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-8569)
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)