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Can I read Phylotypic expression of the bHLH genes \ \ Neurogenin2, Neurod\ \ , and \ \ Mash1\ \ in the mouse embryonic forebrain on EtoBox?
Phylotypic expression of the bHLH genes \ \ Neurogenin2, Neurod\ \ , and \ \ Mash1\ \ in the mouse embryonic forebrain by Joana Osório; Thomas Mueller; Sylvie Rétaux; Philippe Vernier; Mario F. Wullimann is a Neuroscience article available to read on EtoBox.
What is Phylotypic expression of the bHLH genes \ \ Neurogenin2, Neurod\ \ , and \ \ Mash1\ \ in the mouse embryonic forebrain about?
## Abstract In the anamniote model animals, zebrafish and __Xenopus laevis__, highly comparable early forebrain expression patterns of proneural basic helix‐loop‐helix (bHLH) genes relevant for neurogenesis (__atonal__ homologs, i.e., neurogenins/__NeuroD__ and __achaete‐scute__ homologs, i.e., __Ascl/ash)__ were previously revealed during a particular period of development (zebrafish: 3 days; frog: stage 48). Neurogenins/__NeuroD__ on the one hand and __Ascl1/ash1__ on the other hand exhibit essentially mutually exclusive spatial patterns, probably reflecting different positional information received within the neural tube, and appear to underlie glutamatergic versus GABAergic neuronal differentiation, respectively. Significant data suggest that similar complementary localizations of these proneural genes and corresponding differentiation pathways also exist in the mouse, the prominent mammalian model. The present article reports on detailed mouse brain bHLH gene expression patterns to fill existing gaps in the identification of expression domains, especially outside the telencephalon. Clearly, there are strong similarities in the complementarity of territories expressing __Ascl1/
Who reads Phylotypic expression of the bHLH genes \ \ Neurogenin2, Neurod\ \ , and \ \ Mash1\ \ in the mouse embryonic forebrain?
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- Author
- Joana Osório; Thomas Mueller; Sylvie Rétaux; Philippe Vernier; Mario F. Wullimann
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0021-9967)
- Published
- 2010
- Language
- EN
- Field
- Neuroscience (Life Sciences)