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Hepatitis C virus RNA in peripheral blood mononuclear cells: Comparing acute and chronic hepatitis C virus infection by T Chang; K Young; Y Yang; H Lei; H Wu is a Medicine article available to read on EtoBox.

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Hepatitis C virus (HCV) can infect peripheral blood mately 10 kb. 2 Acute posttransfusion hepatitis C mononuclear cells (PBMC) of patients with chronic HCV (PTHC) is followed by chronic hepatitis in about 50% infection. No data are available on PBMC testing for of the cases. Chronic hepatitis may also lead to cirrho-HCV RNA in acute hepatitis C. This study investigated sis and hepatocellular carcinoma in a substantial numthe presence of HCV RNA in PBMC of patients with ber of patients. [5][6][7] Since the isolation of HCV, 2 laboraacute posttransfusion hepatitis C, compared with those tory tests were developed to detect anti-HCV antibodies with chronic HCV infection. Nested polymerase chain in serum. 4 It has been demonstrated that anti-HCV is reaction (PCR) was applied to detect HCV RNA in 111 a useful marker of HCV infection. 1,8 General serological and 48 paired samples of serum and PBMC of 11 patients surveys of HCV infection were undertaken and high with acute posttransfusion hepatitis C and 48 patients seroprevalence rates of HCV were reported among spewith chronic HCV infection, respectively. In patients with acute posttransfusion hepatitis C, HCV RNA was cific risk groups.

Who reads Hepatitis C virus RNA in peripheral blood mononuclear cells: Comparing acute and chronic hepatitis C virus infection?

Author

T Chang; K Young; Y Yang; H Lei; H Wu

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

1996

Language

EN

Field

Medicine (Health Sciences)