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What is DNMT Activity Assay for Epigenetic Research about?

DNA methyltransferases (DNMTs) are enzymes that add methyl groups to cytosine bases in DNA, mainly at CpG sites, creating a chemical mark that usually suppresses gene expression. DNMT1 maintains existing methylation patterns during DNA replication, while DNMT3A and DNMT3B establish new methylation marks during development. These enzymes play key roles in regulating genes, ensuring normal growth, and maintaining genome stability. When DNMT activity becomes abnormal, it can lead to diseases such a

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bhargavughade0

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EN