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Current Concepts of Biomaterial Scaffolds and Regenerative Therapy for Spinal Cord Injury by Hidenori Suzuki; Yasuaki Imajo; Masahiro Funaba; Hiroaki Ikeda; Norihiro Nishida; Takashi Sakai is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Current Concepts of Biomaterial Scaffolds and Regenerative Therapy for Spinal Cord Injury about?

Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological deficit and social and financial burdens. It is currently being managed symptomatically, with no real therapeutic strategies available. In recent years, a number of innovative regenerative strategies have emerged and have been continuously investigated in preclinical research and clinical trials. In the near future, several more are expected to come down the translational pipeline. Among ongoing and completed trials are those reporting the use of biomaterial scaffolds. The advancements in biomaterial technology, combined with stem cell therapy or other regenerative therapy, can now accelerate the progress of promising novel therapeutic strategies from bench to bedside. Various types of approaches to regeneration therapy for SCI have been combined with the use of supportive biomaterial scaffolds as a drug and cell delivery system to facilitate favorable cell–material interactions and the supportive effect of neuroprotection. In this review, we summarize some of the most recent insights of preclinical and clinical studies using biomaterial scaffolds in regenerative therapy for SCI and summar

Who reads Current Concepts of Biomaterial Scaffolds and Regenerative Therapy for Spinal Cord Injury?

Author

Hidenori Suzuki; Yasuaki Imajo; Masahiro Funaba; Hiroaki Ikeda; Norihiro Nishida; Takashi Sakai

Publisher

MDPI AG

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)