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Management of head and neck paragangliomas: Review of 120 patients by Konstantinos Papaspyrou; Wolf J. Mann; Ronald G. Amedee is a Medicine article available to read on EtoBox.

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## Abstract ## Background. Head and neck paragangliomas (PGL) are rare, mostly benign tumors. About 10% to 15% of PGL are caused by mutations in the succinate dehydrogenase genes B, C, or D and may appear multifocally. ## Methods and Results. A retrospective review of 120 patients with 146 head and neck PGL, including 46 carotid body tumors (CBT), 13 vagal tumors, 55 jugulotympanic tumors (JTT), 25 tympanic tumors (TT) and 7 tumors in other locations are included. The internal carotid artery was preserved in 97.5% of CBT resections. Preservation of hearing was achieved in 92% of JTT and 88% of TT resections. ## Conclusion. According to our experience, the treatment of PGL must be individualized, taking into account the patient's age, medical condition, tumor site and size, multiple occurrences, and preexisting cranial nerve deficits. Tumor control is high whether treatment is by surgery or radiotherapy. Patients with solitary lesions whose disease is potentially resectable with acceptable morbidity are better treated surgically. © 2008 Wiley Periodicals, Inc. Head Neck, 2009

Who reads Management of head and neck paragangliomas: Review of 120 patients?

Author

Konstantinos Papaspyrou; Wolf J. Mann; Ronald G. Amedee

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 1043-3074)

Published

2009

Language

EN

Field

Medicine (Health Sciences)