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The document summarizes research on synthesizing and evaluating 5-aza-indeno[1,2-b]fluorine derivatives as potential anticancer agents. Specifically: 1) Researchers reacted 1-indanone with aromatic aldehydes in the presence of ammonium acetate to yield 6,12-Dihydro-5-aza-indeno[1,2-b]fluorine derivatives in good yields. 2) The structures of the compounds were confirmed through various spectral analyses including NMR and X-ray crystallography. 3) Five derivatives were evaluated for in vitro cytotoxicity
- Author
- surendergupta1978
- Language
- EN