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P797 Crohn’s disease and ulcerative colitis was associated with different lipid profile disorders: a nationwide population-based study by H Soh; J Chun; K Han; S Park; E A Kang; J P Im; J S Kim is a Medicine article available to read on EtoBox.

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## Background: The relationships between lipid profiles and the risk for developing inflammatory bowel disease (IBD) including Crohn's disease (CD) and ulcerative colitis (UC) still remains elusive. We conducted a nationwide population-based cohort study to investigate the relationship between lipid profiles and the risk for developing IBD. Methods: We conducted a retrospective study using claims data from the National Healthcare Insurance (NHI) service in Korea. A total of 9,706,026 subjects who received medical check-ups arranged by NHI in 2009 were included and followed up until 2016. Serum lipid profiles, including total cholesterol, triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were collected. Individuals who developed CD and UC were identified during the follow-up. Results: After a mean follow-up of 7.3 years, IBD was detected in 7,058 (0.073%) individuals. IBD group showed a significantly lower prevalence of hypertension, diabetes and dyslipidaemia, compared with non-IBD controls (p-value < 0.001 for each variable). IBD group was inversely associated with serum fasting glucose, serum total cholesterol, LDL-C,

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Author

H Soh; J Chun; K Han; S Park; E A Kang; J P Im; J S Kim

Publisher

Oxford University Press; Oxford University Press (OUP) (ISSN 1873-9946)

Published

2019

Language

EN

Field

Medicine (Health Sciences)