About this Chemistry article
Sythesis of Methylthiomaleimides for the Preparation of Pyridazines and Related Comopounds by Yoshionori Tominaga; Yasuhiro Shigemitsu; Kejni Sasaki is a Chemistry article available to read on EtoBox.
## Abstract New functionalized maleimides (3‐methylthio‐2,5‐dioxo‐1__H__‐pyrroles) were obtained by the reaction of ketene dithioacetals with nitromethane or the reaction of nitro ketene dithioacetal with active methylene compounds in the presence of the appropriate base in dimethyl sulfoxide followed by treatment with methanol. These nakeunudes reacted with various nucleophilic reagents such as election‐rich aromatic and heteroaromatic compounds like dialkylanilines, aminophenols, indoles, indolizines, and cyalazines to give the corresponding 3‐aryl‐ or heteroaryl‐ 1__H__‐pyrole‐2,5‐diones. Styryl and merocyanie dyes, and polycyclic pyridazine‐diones as chemiluminophors and succinimides were also obtained from these maleimides with good results.
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- Author
- Yoshionori Tominaga; Yasuhiro Shigemitsu; Kejni Sasaki
- Publisher
- Journal of Heterocyclic Chemistry; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley; FASEB (ISSN 0022-152X)
- Published
- 2002
- Language
- EN
- Field
- Chemistry (Physical Sciences)