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Cortical laminar necrosis in brain infarcts: serial MRI by N. Siskas; A. Lefkopoulos; I. Ioannidis; A. Charitandi; A. Dimitriadis is a Medicine article available to read on EtoBox.

What is Cortical laminar necrosis in brain infarcts: serial MRI about?

## Patients and methods From March 1998 to February 2001, reviewing 60 patients diagnosed as having brain infarcts on clinical features and CT, we found 12 (four women, eight men), aged 23-83 years, with laminar high-signal lesions on T1-weighted images. The inclusion criterion was the presence of high-signal laminar cortical lesions on T1 weighted images at any time during the clinical course. Patients with calcification or haemorrhagic infarcts on CT were excluded. All patients underwent CT within 24 h of admission and on the day of their first MRI. Each underwent serial MRI from day 6 to 1.5 years after the ictus, at 1.5 tesla. The basic protocol included T1-weighted and T2-weighted axial spin-echo images, and contrast enhancement with gadolinium diethylenetriamine-pentaacetic acid (Gd-DTPA) 0.1-0.2 mmol/kg. Fluid-attenuated inversion-recovery (FLAIR) and T2\*-weighted gradient-echo images were performed in some cases, the former on seven occasions for five patients, latter on three occasions for three patients. T1-weighted spin-echo images with fat suppression were obtained in two patients. The imaging parameters were: T1-weighted images: TR 510-655 TE 14-16 ms, two excitations

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Author
N. Siskas; A. Lefkopoulos; I. Ioannidis; A. Charitandi; A. Dimitriadis
Publisher
Springer Science and Business Media LLC
Published
2003
Language
EN
Field
Medicine (Health Sciences)

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