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Enhancing β-Lactam Sensitivity in P. aeruginosa by weijiankong12 is a document available to read on EtoBox.
This research investigates the role of membrane-bound lytic transglycosylases (mLTs) in the antibiotic resistance of Pseudomonas aeruginosa, focusing on their impact on outer membrane permeability and β-lactam sensitivity. The study finds that loss of specific mLTs increases β-lactam minimum inhibitory concentrations (MICs) and enhances sensitivity to other antibiotics, suggesting that mLTs contribute to cell envelope stability. The findings indicate that targeting lytic transglycosylases, particularly Slt,
- Author
- weijiankong12
- Language
- EN